Figure 1.
Fig. 1. Atomic structures of HisA (upper panel) and HisF (lower
panel) from Thermotoga maritima in ribbon presentations (29).
View from the COOH-terminal face of the central barrel,
left; side view, center; and view from the NH[2]-terminal face
of the barrel, right. HisF contains two phosphate ions bound to
the active site, shown as space-filling models (red). The strands
and helices
of the central eightfold / barrel are
in orange and yellow, respectively. Loops at the NH[2]- and
COOH-terminal faces of the barrel are in cyan and green,
respectively. Some loops contain additional secondary structural
elements. The NH[2]- and COOH-termini are labeled when visible.
The above figure is reprinted
by permission from the AAAs:
Science
(2000,
289,
1546-1550)
copyright 2000.
barrel,
left; side view, center; and view from the NH[2]-terminal face
of the barrel, right. HisF contains two phosphate ions bound to
the active site, shown as space-filling models (red). The 
helices
of the central eightfold