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Figure 1.
Figure 1. Overall architecture of human Pin1. a, Ribbon
representation of the Pin1 -CTD peptide complex. Residues 1 -5
of Pin1 are visible in the electron density maps but not shown
here for clarity; residues 39 -50 are disordered. Apostrophes
distinguish the WW domain colored purple from the PPIase domain
colored blue. The CTD peptide backbone is yellow. Residues of
the CTD peptide are labeled with primes. Atoms are colored
according to type: carbon, light gray; nitrogen, blue;
phosphorus, black; oxygen, red; sulfur, yellow. Dotted green
lines depict hydrogen bonds. b, Ribbon representation of the
Pin1 -PEG complex19. c, Stereo view of the SIGMAA weighted
|2F[o] - F[c]| electron density map contoured at 1.0  around
the Tyr 23-Trp 34 clamp.
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