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Figure 1.
Figure 1. (a) Stereo surface representation of the 1F9/TEL
complex. The V[H] domain is orange, the V[L] domain is gray and
TEL, which is separated by 10 Å for better clarity of the
contact surface is shown in red. The residues indicated in blue
are involved in the antigen-antibody interaction (Table 2). The
representation was drawn with WebLab ViewerPro [Molecular
Simulation 1999]. The buried solvent-accessible surface area
calculated with the program AREAIMOL [Collaborative
Computational Project 1994]. (b) Stereo-view of the tube
a-carbon trace of 1F9/TEL complex. The CDR regions of the V[H]
domain are shown yellow, and the CDR regions of the V[L] domain
are shown light gray. TEL is least-squares superimposed with the
uncomplexed TEL (PDB entry 135L, [Harata 1993]) in light blue
and uncomplexed HEL (PDB entry 1AKI, [Artymiuk et al 1982]) in
blue calculated by the program LSQKAB [Collaborative
Computational Project 1994]. This and the following presentation
are drawn with SETOR [Evans 1993]. (c) Stereo-view of the
interaction region with the side-chain contacts of the lysozyme
residue 101 (Gly in TEL, Asp in HEL) with CDR L1 and H3.
Hydrogen bonds are marked in black.
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