Figure 1.
Figure 1 p40 resembles a soluble class 1 cytokine -receptor.
N- and C-termini are labeled N and C, respectively, and the
three domains are labeled D1, D2 and D3. The intrachain
disulfide bonds (yellow), an N-linked sugar modification (red)
and the WSXWS motif (magenta) are shown. The p40 loops that
contact p35 (turquoise) are located at the apex between D2 and
D3. Flexible loop regions are indicated by dotted lines. This
and all subsequent figures (except Figures 3 and 7) were made
using MOLSCRIPT (Kraulis, 1991) and Raster3D (Merritt and Bacon,
1997).
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(2000,
19,
3530-3541)
copyright 2000.
-receptor.
N- and C-termini are labeled N and C, respectively, and the
three domains are labeled D1, D2 and D3. The intrachain
disulfide bonds (yellow), an N-linked sugar modification (red)
and the WSXWS motif (magenta) are shown. The p40 loops that
contact p35 (turquoise) are located at the apex between D2 and
D3. Flexible loop regions are indicated by dotted lines. This
and all subsequent figures (except Figures 3 and 7) were made
using MOLSCRIPT (Kraulis, 1991) and Raster3D (Merritt and Bacon,
1997).