Figure 1 - full size

 

Figure 1.
Fig. 1. Structure of the T1[4] [4] complex. (A) Ribbon representation showing four contact loops that form the primary interface between the T1 and tetramers. The T1 tetramer is red and the tetramer is blue. (B) Molecular detail of a T1 contact loop touching the subunit surface (24). (C) Stereoview of a C trace of the tetramer (blue) and T1 tetramer (red) viewed along the four-fold axis and showing the relative proximity of the NH[2]-termini of each where inactivation gates are attached. The NADP+ cofactor in each active site is green. This figure was generated with the programs O (25), MOLSCRIPT (26), Raster-3D (27), and POVRAY (28).

The above figure is reprinted by permission from the AAAs: Science (2000, 289, 123-127) copyright 2000.