Figure 1 - full size

 

Figure 1.
Figure 1. The Crystal Structure of the Hammerhead Ribozyme(A) shows the three-dimensional crystal structure of the hammerhead ribozyme in its initial state conformation. (B) is a schematic diagram of this structure designed to complement (A). The enzyme strand is shown in red, the substrate strand in yellow, and the cleavage site base in green. Base pairing is indicated by white lines (with broken lines indicating noncanonical single H bond contacts), and pink lines indicate base–ribose interactions.

The above figure is reprinted by permission from Cell Press: Mol Cell (2000, 5, 279-287) copyright 2000.