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Figure 1.
Figure 1. Sequence Homology of eIF1A-like Proteins across
All KingdomsSequence alignments adapted from the paper by [25].
Amino acids that have greater than 50% identity over 12
sequences analyzed by Kyrpides (more than shown in figure) are
shaded. Identities between human and yeast are shown with black
circles (65% identity). Side bars indicate sequences from
eukaryotes (E), archaebacteria (A), and eubacteria (B/IF1). The
secondary structure of human eIF1A (determined in this paper)
over the region that has observable long-range NOEs is shown
below the sequence (wavy lines indicate coils or turns; arrows
indicate strands; cylinders indicate helices). The secondary
structure elements are labeled β for β strand, α for α and
3[10] helices, L for loops connecting β strands or helices, N
for amino-terminal strand, C for carboxy-terminal strand. Loop
numbering indicates the secondary structure elements connect by
the loops (adapted from [32]). For instance, L12 connects strand
1 and 2, and L3α connects strand 3 and the subsequent helix 1.
Organisms are: HUMAN, Homo sapiens; YEAST, Saccharomyces
cerevisiae; METJA, Methanococcus jannaschii; ARCFU,
Archaeoglobus fulgidus; ECOLI, Escherichia coli; BACSU, Bacillus
subtilis.
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