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Figure 1.
Fig. 1. MOLSCRIPT diagrams (15, 16) of pNB esterases
looking into the active site cavity, showing loops that are not
visible in the electron density as dashed lines and loops that
reorganize most significantly in gold. The catalytic triad is
shown in red and mutations are shown in blue. (A) The WT
structure with secondary structural elements labeled. (B) The
5-6c8 structure. (C) The 8g8 structure, rotated slightly from
the others to clarify the location of the mutations. (D) A
wall-eyed stereo overlay of the C[  ]positions
of the three structures, oriented as in A and B. WT is shown in
blue, organophile 5-6c8 in green, and thermophile 8g8 in purple.
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