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Title
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Structural similarities between fructose-1,6-bisphosphatase and inositol monophosphatase.
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Authors
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Y.Zhang,
J.Y.Liang,
W.N.Lipscomb.
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Ref.
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Biochem Biophys Res Commun, 1993,
190,
1080-1083.
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PubMed id
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Abstract
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Fructose-1,6-bisphosphatase and inositol monophosphatase are found to share a
similar secondary structure topology even though their sequences have very
limited homology. Both enzymes have a layered alpha beta alpha beta alpha type
structure and similar tertiary structures. All but one of the metal binding
residues are conserved between these two enzymes and homologous proteins. The
exception is Glu-280 in fructose-1,6-bisphosphatase to Asp-220 in inositol
monophosphatase.
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