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Title
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Structure of adenovirus fibre. II. Morphology of single fibres.
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Authors
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R.W.Ruigrok,
A.Barge,
C.Albiges-Rizo,
S.Dayan.
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Ref.
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J Mol Biol, 1990,
215,
589-596.
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PubMed id
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Abstract
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Adenovirus type 2 fibres in crystals appear to be significantly longer than
found previously (accompanying paper). We therefore examined isolated fibre by
electron microscopy and measured a length of 370 A, consistent with the length
found in the crystals. The specific N-terminal structure of the fibre caused a
heterogeneity in the length that may at least partially explain the values of
280 to 310 A published previously. Green et al. described a 15 amino acid repeat
in the primary structure of the shaft of the fibre thought to be associated with
the specific three-dimensional folding of the shaft. We compared the adenovirus
type 2 (with 22 repeats) and type 3 (with 6 repeats) fibre lengths and derived a
contribution of 13.2 A to the length of the shaft per 15 amino acid repeat.
Specific morphological features of the fibre are discussed in relation to its
amino acid sequence.
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