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Title
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Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibre.
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Authors
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P.Guardado-Calvo,
A.L.Llamas-Saiz,
G.C.Fox,
J.N.Glasgow,
M.J.van Raaij.
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Ref.
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Acta Crystallogr Sect F Struct Biol Cryst Commun, 2009,
65,
1149-1152.
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PubMed id
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Abstract
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The porcine adenovirus NADC-1 isolate, a strain of porcine adenovirus type 4,
has a fibre with an atypical architecture. In addition to a classical virus
attachment region, shaft and head domains, it contains an additional galectin
like domain C-terminal to the head domain and connected to the head domain by a
long RGD-containing loop. The galectin-like domain contains two putative
carbohydrate-recognition domains. The head and galectin-like domains have been
independently crystallized. Diffraction data have been obtained to 3.2 angstrom
resolution from crystals of the head domain and to 1.9 angstrom resolution from
galectin-like domain crystals.
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