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Title
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[Spatial structure of a Fab-fragment of a monoclonal antibody to human interleukin-2 in two crystalline forms at a resolution of 2.2 and 2.9 angstroms].
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Authors
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A.V.Fokin,
P.V.Afonin,
I.I.u.Mikhaĭlova,
I.N.Tsygannik,
T.I.u.Mareeva,
V.A.Nesmeianov,
W.Pangborn,
N.Lee,
W.Duax,
E.Siszak,
V.Z.Pletnev.
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Ref.
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Bioorg Khim, 2000,
26,
571-578.
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PubMed id
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Abstract
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The three-dimensional structure of the antigen-binding fragment of a monoclonal
antibody to human interleukin-2 was determined in two crystal forms by the X-ray
method of molecular replacement at 2.2 and 2.9 A resolutions. The spatial
structure of the protein and the stereochemistry of its antigen-binding site
were analyzed.
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