UniProt functional annotation for O27818

UniProt code: O27818.

Organism: Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
Taxonomy: Archaea; Euryarchaeota; Methanomada group; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
 
Function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. {ECO:0000269|PubMed:10827167}.
 
Catalytic activity: Reaction=dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta- L-rhamnose; Xref=Rhea:RHEA:16969, ChEBI:CHEBI:57649, ChEBI:CHEBI:62830; EC=5.1.3.13; Evidence={ECO:0000269|PubMed:10827167};
Pathway: Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis. {ECO:0000250|UniProtKB:P26394}.
Subunit: Homodimer. {ECO:0000269|PubMed:10827167}.
Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.