UniProt functional annotation for P47992

UniProt code: P47992.

Organism:		Homo sapiens (Human).
Taxonomy:		Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Function:		Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment. {ECO:0000250|UniProtKB:P47993}.
Subcellular location:		Secreted.
Tissue specificity:		Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.
Similarity:		Belongs to the intercrine gamma family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.