PDBsum entry 9v0u

Membrane protein

PDB id: 9v0u

Contents

Protein chains

270 a.a.

205 a.a.

55 a.a.

334 a.a.

PDB id:

9v0u

Name:

Membrane protein

Title:

Gpr133-gain-minig13 complex

Structure:

Adhesion g-protein coupled receptor d1. Chain: r. Synonym: g-protein coupled receptor 133,g-protein coupled receptor pgr25. Engineered: yes. Guanine nucleotide-binding protein subunit alpha-13,isoform 2 of guanine nucleotide-binding protein subunit alpha-13. Chain: a. Synonym: g alpha-13,g-protein subunit alpha-13.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: adgrd1, gpr133, pgr25. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gna13. Gene: gng2. Gene: gnb1.

Authors:

Y.Xi,X.Pu,Y.Ping

Key ref:

X.Pu et al. (2025). Cryo-Em structural elucidation and molecular mechanis the gpr133-G13 signaling complex.. Biochem.Biophys.Res.Commun., 777, 52165. PubMed id: 40570642 DOI: 10.1016/J.BBRC.2025.152165

Date:

19-May-25 Release date: 30-Jul-25

Protein chain

Q6QNK2  (AGRD1_HUMAN) -  Adhesion G-protein coupled receptor D1 from Homo sapiens

Seq: 874 a.a.

Struc: 270 a.a.

Protein chain

Q14344  (GNA13_HUMAN) -  Guanine nucleotide-binding protein subunit alpha-13 from Homo sapiens

Seq: 377 a.a.

Struc: 205 a.a.*

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 55 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 334 a.a.

* PDB and UniProt seqs differ at 42 residue positions (black crosses)