PDBsum entry 9l3w

Membrane protein

PDB id: 9l3w

Contents

Protein chains

205 a.a.

335 a.a.

54 a.a.

108 a.a.

281 a.a.

PDB id:

9l3w

Name:

Membrane protein

Title:

Cryo-em structure of the chemokine-like receptor 1 in complex with chemerin and gi1

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Mutation: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Gene: rarres2, tig2.

Authors:

Y.Zhu,M.He,B.Wu,Q.Zhao

Key ref:

X.Lin et al. Structural insights into the distinct ligand recognit signaling of the chemerin receptors cmklr1 and gpr1.. Protein cell, . PubMed id: 39752296

Date:

19-Dec-24 Release date: 12-Mar-25

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 205 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 335 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 54 a.a.

Protein chain

Q99969  (RARR2_HUMAN) -  Retinoic acid receptor responder protein 2 from Homo sapiens

Seq: 163 a.a.

Struc: 108 a.a.

Protein chain

Q99788  (CML1_HUMAN) -  Chemerin-like receptor 1 from Homo sapiens

Seq: 373 a.a.

Struc: 281 a.a.

* PDB and UniProt seqs differ at 5 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????