PDBsum entry 9jg0

Membrane protein

PDB id: 9jg0

Contents

Protein chains

400 a.a.

218 a.a.

120 a.a.

212 a.a.

PDB id:

9jg0

Name:

Membrane protein

Title:

Cryo-em structure of neuropeptide ff receptor 2 in the ligand-free state with bril fusion, anti-bril fab, and nanobody

Structure:

Isoform 2 of neuropeptide ff receptor 2,soluble cytochrome b562. Chain: r. Synonym: g-protein coupled receptor 74,g-protein coupled receptor hlwar77,neuropeptide g-protein coupled receptor,cytochrome b-562. Engineered: yes. Other_details: 246 to 363 is soluble cytochrome b562 with linker. Anti-bril fab heavy chain. Chain: h.

Source:

Homo sapiens, escherichia coli. Human. Organism_taxid: 9606, 562. Gene: npffr2, gpr74, npff2, npgpr, cybc. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Homo sapiens. Organism_taxid: 9606. Expressed in: trichoplusia ni.

Authors:

J.Kim,H.-J.Choi

Key ref:

J.Kim et al. Structural insights into the selective recognition of rf-Amide peptides by neuropeptide ff receptor 2.. Embo rep, . PubMed id: 40128413

Date:

05-Sep-24 Release date: 09-Apr-25

Protein chain

Q9Y5X5  (NPFF2_HUMAN) -  Neuropeptide FF receptor 2 from Homo sapiens

Seq: 522 a.a.

Struc: 400 a.a.*

Protein chain

No UniProt id for this chain

Struc: 218 a.a.

Protein chain

No UniProt id for this chain

Struc: 120 a.a.

Protein chain

No UniProt id for this chain

Struc: 212 a.a.

* PDB and UniProt seqs differ at 97 residue positions (black crosses)