PDBsum entry 9jft

Signaling protein/immune system

PDB id: 9jft

Contents

Protein chains

232 a.a.

339 a.a.

56 a.a.

128 a.a.

282 a.a.

PDB id:

9jft

Name:

Signaling protein/immune system

Title:

Cryo-em structure of gpr65 complexed with minigs in ph6.5

Structure:

Guanine nucleotide-binding protein g(s) subunit alpha isoforms short. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Lama glama. Organism_taxid: 9844.

Authors:

X.L.Yue,L.J.Wu,T.Hua,Z.J.Liu

Key ref:

X.Yue et al. (2025). Structural basis of stepwise proton sensing-Mediated activation.. Cell res., 35, 423. PubMed id: 40211064 DOI: 10.1038/S41422-025-01092-W

Date:

05-Sep-24 Release date: 13-Aug-25

Protein chain

No UniProt id for this chain

Struc: 232 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 339 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 56 a.a.

Protein chain

No UniProt id for this chain

Struc: 128 a.a.

Protein chain

Q8IYL9  (PSYR_HUMAN) -  G-protein coupled receptor 65 from Homo sapiens

Seq: 337 a.a.

Struc: 282 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)