PDBsum entry 9j0f

Membrane protein

PDB id: 9j0f

Contents

Protein chains

217 a.a.

337 a.a.

56 a.a.

295 a.a.

Ligands

NAI

PDB id:

9j0f

Name:

Membrane protein

Title:

Nadh bound purinergic receptor p2y14 in complex with gi

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gnb1. Gene: gng2. Escherichia coli, homo sapiens.

Authors:

T.X.Wang,Q.C.Gu,W.Q.Tang

Key ref:

Q.Gu et al. (2025). Structural insights into ligand recognition and activ of human purinergic receptor p2y14.. Cell discov, 11, 48. PubMed id: 40360473 DOI: 10.1038/S41421-025-00799-9

Date:

02-Aug-24 Release date: 04-Jun-25

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 217 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 337 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 56 a.a.

Protein chain

Q15391  (P2Y14_HUMAN) -  P2Y purinoceptor 14 from Homo sapiens

Seq: 338 a.a.

Struc: 295 a.a.

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????