PDBsum entry 9ixj

Membrane protein/immune system

PDB id: 9ixj

Contents

Protein chains

231 a.a.

340 a.a.

55 a.a.

128 a.a.

275 a.a.

Ligands

HSM

CLR

PDB id:

9ixj

Name:

Membrane protein/immune system

Title:

Histamine-bound h2r in complex with gs

Structure:

Guanine nucleotide-binding protein g(s) subunit alpha isoforms short. Chain: a. Synonym: guanine nucleotide-binding protein g(s) subunit alpha (4a), adenylate cyclase-stimulating g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnas, gnas1, gsp. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Lama glama.

Authors:

Y.He,K.Chen

Key ref:

Y.He and k.chen Histamine-Bound h2r in complex with gs. To be published, .

Date:

28-Jul-24 Release date: 30-Jul-25

Protein chain

P63092  (GNAS2_HUMAN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Homo sapiens

Seq: 394 a.a.

Struc: 231 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 340 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 55 a.a.

Protein chain

No UniProt id for this chain

Struc: 128 a.a.

Protein chain

P25021  (HRH2_HUMAN) -  Histamine H2 receptor from Homo sapiens

Seq: 359 a.a.

Struc: 275 a.a.

* PDB and UniProt seqs differ at 48 residue positions (black crosses)