PDBsum entry 9iv1

Membrane protein

PDB id: 9iv1

Contents

Protein chains

231 a.a.

338 a.a.

58 a.a.

255 a.a.

227 a.a.

Ligands

DHT

PDB id:

9iv1

Name:

Membrane protein

Title:

Identification, structure and agonist design of an androgen membrane receptor.

Structure:

Scfv16. Chain: s. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit

Source:

Synthetic construct. Organism_taxid: 32630. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Homo sapiens. Human. Organism_taxid: 9606. Gene: gnb1. Gene: gng2.

Authors:

Y.Q.Ping,Z.Yang

Key ref:

Z.Yang et al. Identification, Structure, And agonist design of an a membrane receptor.. Cell, . PubMed id: 39884271

Date:

22-Jul-24 Release date: 12-Feb-25

Protein chain

No UniProt id for this chain

Struc: 231 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 338 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 58 a.a.

Protein chain

Q6QNK2  (AGRD1_HUMAN) -  Adhesion G-protein coupled receptor D1 from Homo sapiens

Seq: 874 a.a.

Struc: 255 a.a.

Protein chain

P63092  (GNAS2_HUMAN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Homo sapiens

Seq: 394 a.a.

Struc: 227 a.a.*

* PDB and UniProt seqs differ at 53 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????