PDBsum entry 9ew2

Membrane protein

PDB id: 9ew2

Contents

Protein chains

234 a.a.

337 a.a.

57 a.a.

126 a.a.

336 a.a.

PDB id:

9ew2

Name:

Membrane protein

Title:

High resolution structure of fzd7 in complex with minigs protein

Structure:

Gnas complex locus,isoform 4 of guanine nucleotide-binding protein g(s) subunit alpha isoforms short. Chain: a. Synonym: adenylate cyclase-stimulating g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnas, gnas, gnas1, gsp. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: fzd7. Expression_system_taxid: 7108

Authors:

J.Bous,J.Kinsolving,L.Gratz,M.M.Scharf,J.Voss,B.Selcuk,O.Adebali, G.Schulte

Key ref:

J.Bous et al. High resolution structure of fzd7 in complex with min protein. To be published, . PubMed id: 39198452

Date:

03-Apr-24 Release date: 02-Oct-24

Protein chain

P63092  (GNAS2_HUMAN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Homo sapiens

Seq: 394 a.a.

Struc: 234 a.a.*

Protein chain

Q5JWD1  (Q5JWD1_HUMAN) -  GNAS complex locus from Homo sapiens

Seq: 87 a.a.

Struc: 234 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 337 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 57 a.a.

Protein chain

No UniProt id for this chain

Struc: 126 a.a.

Protein chain

O75084  (FZD7_HUMAN) -  Frizzled-7 from Homo sapiens

Seq: 574 a.a.

Struc: 336 a.a.

* PDB and UniProt seqs differ at 28 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????