PDBsum entry 9d4z

Immune system

PDB id: 9d4z

Contents

Protein chains

303 a.a.

24 a.a.

297 a.a.

231 a.a.

212 a.a.

PDB id:

9d4z

Name:

Immune system

Title:

Cryoem structure of par1 with endogenous tethered ligand

Structure:

Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2. Chain: g. Synonym: g gamma-i.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnb1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gng2. Gene: f2r, cf2r, par1, tr. Mus musculus.

Authors:

X.Lyu,Z.Lyu,A.P.Mcgrath,Y.Kang

Key ref:

Z.Lyu et al. (2025). Structural basis for the activation of proteinase-Act receptors par1 and par2.. Nat commun, 16, 3931. PubMed id: 40287415

Date:

13-Aug-24 Release date: 07-May-25

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 303 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 24 a.a.

Protein chain

P25116  (PAR1_HUMAN) -  Proteinase-activated receptor 1 from Homo sapiens

Seq: 425 a.a.

Struc: 297 a.a.*

Protein chain

No UniProt id for this chain

Struc: 231 a.a.

Protein chain

No UniProt id for this chain

Struc: 212 a.a.

* PDB and UniProt seqs differ at 6 residue positions (black crosses)