PDBsum entry 9bi6

Signaling protein

PDB id: 9bi6

Contents

Protein chains

193 a.a.

299 a.a.

21 a.a.

115 a.a.

285 a.a.

Ligands

Y01

PDB id:

9bi6

Name:

Signaling protein

Title:

Human proton sensing receptor gpr68 in complex with minigsq

Structure:

Minigsq. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit

Source:

Synthetic construct. Organism_taxid: 32630. Expressed in: homo sapiens. Expression_system_taxid: 9606. Homo sapiens. Human. Organism_taxid: 9606. Gene: gnb1. Expressed in: trichoplusia ni.

Authors:

M.K.Howard,N.Hoppe,X.P.Huang,C.B.Macdonald,E.Mehrotra,P.Rockefeller Grimes,A.M.Zahm,D.D.Trinidad,J.English,W.Coyote-Maestas,A.Manglik

Key ref:

M.K.Howard et al. Molecular basis of proton sensing by g protein-Couple receptors.. Cell, . PubMed id: 39753132

Date:

22-Apr-24 Release date: 15-Jan-25

Protein chain

No UniProt id for this chain

Struc: 193 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 299 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 21 a.a.

Protein chain

No UniProt id for this chain

Struc: 115 a.a.

Protein chain

Q15743  (OGR1_HUMAN) -  Ovarian cancer G-protein coupled receptor 1 from Homo sapiens

Seq: 365 a.a.

Struc: 285 a.a.