PDBsum entry 9b9y

Signaling protein/immune system

PDB id: 9b9y

Contents

Protein chains

478 a.a.

123 a.a.

Ligands

7DY

PDB id:

9b9y

Name:

Signaling protein/immune system

Title:

Structural mechanism of cb1r binding to peripheral and biased inverse agonists

Structure:

Cannabinoid receptor 1,glycogen synthase. Chain: r. Synonym: cb-r,cb1,cann6. Engineered: yes. Cnb36. Chain: n. Engineered: yes

Source:

Homo sapiens, pyrococcus abyssi ge5. Human. Organism_taxid: 9606, 272844. Gene: cnr1, cnr, pab2292. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Lama glama. Llama. Organism_taxid: 9844.

Authors:

P.Kumari,S.Dvoracsko,M.D.Enos,K.Ramesh,D.Lim,S.A.Hassan,G.Kunos, M.R.Iyer,D.M.Rosenbaum

Key ref:

P.Kumari et al. Structural mechanism of cb1r binding to peripheral an biased inverse agonists. To be published, . PubMed id: 39695122

Date:

03-Apr-24 Release date: 20-Nov-24

Protein chain

P21554  (CNR1_HUMAN) -  Cannabinoid receptor 1 from Homo sapiens

Seq: 472 a.a.

Struc: 478 a.a.*

Protein chain

Q9V2J8  (Q9V2J8_PYRAB) -  Glycogen synthase from Pyrococcus abyssi (strain GE5 / Orsay)

Seq: 437 a.a.

Struc: 478 a.a.*

Protein chain

No UniProt id for this chain

Struc: 123 a.a.

* PDB and UniProt seqs differ at 396 residue positions (black crosses)