PDBsum entry 9ast

Signaling protein

PDB id: 9ast

Contents

Protein chains

218 a.a.

11 a.a.

283 a.a.

336 a.a.

54 a.a.

232 a.a.

PDB id:

9ast

Name:

Signaling protein

Title:

Cryo-em structure of xcr1 signaling complex

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Mutation: yes. Lymphotactin. Chain: l. Synonym: atac,c motif chemokine 1,cytokine scm-1,lymphotaxin,scm-1- alpha,small-inducible cytokine c1,xc chemokine ligand 1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: xcl1, ltn, scyc1. Gene: xcr1, ccxcr1, gpr5. Gene: gnb1.

Authors:

X.Zhang,C.Zhang

Key ref:

X.Zhang et al. (2024). Molecular basis for chemokine recognition and activat xcr1.. Proc.Natl.Acad.Sci.Usa, 121, 32121. PubMed id: 39565315 DOI: 10.1073/PNAS.2405732121

Date:

26-Feb-24 Release date: 11-Dec-24

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 218 a.a.*

Protein chain

P47992  (XCL1_HUMAN) -  Lymphotactin from Homo sapiens

Seq: 114 a.a.

Struc: 11 a.a.

Protein chain

P46094  (XCR1_HUMAN) -  Chemokine XC receptor 1 from Homo sapiens

Seq: 333 a.a.

Struc: 283 a.a.

Protein chain

A0A482LYE4  () -  Non structural polyprotein (Fragment) from Ross River virus

Seq: 261 a.a.

Struc: 283 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 336 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 54 a.a.*

Protein chain

No UniProt id for this chain

Struc: 232 a.a.

* PDB and UniProt seqs differ at 154 residue positions (black crosses)