PDBsum entry 8vq7

Lyase/inhibitor

PDB id: 8vq7

Contents

Protein chain

257 a.a.

Metals

_ZN

Waters ×308

PDB id:

8vq7

Name:

Lyase/inhibitor

Title:

Hca-ii-apo structure

Structure:

Carbonic anhydrase 2. Chain: a. Synonym: carbonate dehydratase ii, carbonic anhydrasE C, cac, carbonic anhydrase ii, ca-ii. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008

Resolution:

1.41Å R-factor: 0.133 R-free: 0.172

Authors:

M.M.Ismail

Key ref:

M.M.Ismail Sbdd of carbonic anhydrase ii inhibitors. To be published, .

Date:

17-Jan-24 Release date: 16-Jul-25

Protein chain

P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2 from Homo sapiens

Seq: 260 a.a.

Struc: 257 a.a.

Enzyme reactions

• Enzyme class: E.C.4.2.1.1 - carbonic anhydrase.
• Reaction: hydrogencarbonate + H⁺ = CO2 + H2O
• Cofactor: Zn(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site