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UniProt functional annotation for Q9Y2U9 | ||
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| UniProt code: Q9Y2U9. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Represses CREB3-mediated transcription by interfering with CREB3-DNA binding. {ECO:0000269|PubMed:11384994}. |
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| Subunit: | |
Directly interacts with CREB3, but not with CREB1, ATF4, ATF6, JUN, FOS, CEBPA and herpes simplex virus transactivator VP16. {ECO:0000269|PubMed:11384994}. |
| Subcellular location: | |
Nucleus {ECO:0000269|PubMed:11384994}. |
| Tissue specificity: | |
Widely expressed, with high levels in skeletal muscle, heart, pancreas and liver. Undetectable in peripheral blood leukocytes. {ECO:0000269|PubMed:11384994, ECO:0000269|PubMed:16964437}. |
Annotations taken from UniProtKB at the EBI.