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UniProt functional annotation for P0CI78 | ||
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| UniProt code: P0CI78. |
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| Organism: | |
Bacillus subtilis (strain 168). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus. |
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| Function: | |
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. {ECO:0000250}. |
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| Function: | |
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. {ECO:0000250}. |
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| Function: | |
Has also been isolated as a basic, heat-shock stable DNA- binding protein from the B.subtilis nucleoid. It binds cooperatively to double-stranded supercoiled DNA which it further compacts into complexes 15-17 nm in diameter. Overexpression of the protein disrupts nucleoid segregation and positioning. |
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| Subunit: | |
Part of the 50S ribosomal subunit. {ECO:0000269|PubMed:30126986}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:11278078}. Cytoplasm, nucleoid {ECO:0000269|PubMed:11278078}. Note=Is located predominantly at the nucleoid poles during exponential phase, while in stationary phase the protein is more evenly distributed in the whole cell. |
| Similarity: | |
Belongs to the universal ribosomal protein uL24 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.