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UniProt functional annotation for Q7Z5G4 | ||
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| UniProt code: Q7Z5G4. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS. {ECO:0000269|PubMed:14522980, ECO:0000269|PubMed:16000296}. |
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| Subunit: | |
Interacts with GOLGA3. Interacts with ZDHHC9. {ECO:0000269|PubMed:14522980, ECO:0000269|PubMed:16000296}. |
| Subcellular location: | |
Golgi apparatus membrane {ECO:0000269|PubMed:14522980, ECO:0000269|PubMed:16000296}; Lipid- anchor {ECO:0000269|PubMed:14522980, ECO:0000269|PubMed:16000296}. |
| Tissue specificity: | |
Expressed in all tissues except colon and thymus. {ECO:0000269|PubMed:14522980, ECO:0000269|PubMed:16000296}. |
| Ptm: | |
Palmitoylated on Cys-69 and Cys-72; which is required for Golgi localization and interaction with GOLGA3. {ECO:0000269|PubMed:14522980}. |
| Similarity: | |
Belongs to the ERF4 family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=AAD39919.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=AAF65180.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.