PDBsum entry 8zbi

Membrane protein

PDB id: 8zbi

Contents

Protein chains

112 a.a.

312 a.a.

36 a.a.

231 a.a.

281 a.a.

12 a.a.

PDB id:

8zbi

Name:

Membrane protein

Title:

Cryo-em structure of somatostatin receptor 3 (sstr3) with gi1 complex

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: b. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: c. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Gene: cybc, sstr3.

Authors:

J.H.Yun

Key ref:

Y.Heo et al. The structures of sstr3 and sstr5 provide insights in specificity among somatostatin receptors. To be published, .

Date:

26-Apr-24 Release date: 30-Apr-25

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 112 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 312 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 36 a.a.

Protein chain

No UniProt id for this chain

Struc: 231 a.a.

Protein chain

P0ABE7  (C562_ECOLX) -  Soluble cytochrome b562 from Escherichia coli

Seq: 128 a.a.

Struc: 281 a.a.*

Protein chain

P32745  (SSR3_HUMAN) -  Somatostatin receptor type 3 from Homo sapiens

Seq: 418 a.a.

Struc: 281 a.a.

Protein chain

P61278  (SMS_HUMAN) -  Somatostatin from Homo sapiens

Seq: 116 a.a.

Struc: 12 a.a.

* PDB and UniProt seqs differ at 116 residue positions (black crosses)