PDBsum entry 8y62

Membrane protein

PDB id: 8y62

Contents

Protein chains

215 a.a.

336 a.a.

54 a.a.

231 a.a.

292 a.a.

Ligands

16C

PDB id:

8y62

Name:

Membrane protein

Title:

Cryo-em structure of the c16:0 ceramide-bound fpr2-gi complex

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Synthetic construct.

Authors:

J.P.Sun,C.T.Jiang,W.Kong,X.Yu,K.Cai,L.L.Guo

Key ref:

J.P.Sun et al. Cryo-Em structure of the c16:0 fatty acid-Bound fpr2- Complex. To be published, . PubMed id: 40080544

Date:

01-Feb-24 Release date: 05-Feb-25

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 215 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 336 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 54 a.a.

Protein chain

No UniProt id for this chain

Struc: 231 a.a.

Protein chain

P25090  (FPR2_HUMAN) -  N-formyl peptide receptor 2 from Homo sapiens

Seq: 351 a.a.

Struc: 292 a.a.

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????