PDBsum entry 8x3l

Membrane protein/immune system

PDB id: 8x3l

Contents

Protein chains

218 a.a.

338 a.a.

57 a.a.

287 a.a.

230 a.a.

Ligands

XWD

PDB id:

8x3l

Name:

Membrane protein/immune system

Title:

Cryo-em structure of cb2-g protein complex

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Gene: cnr2.

Authors:

S.Y.Shen,Z.Q.Yang,Z.H.Shao

Key ref:

S.Y.Shen et al. Cryo-Em structure of cb2-G protein complex. To be published, . PubMed id: 39024109

Date:

14-Nov-23 Release date: 20-Nov-24

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 218 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 338 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 57 a.a.

Protein chain

P34972  (CNR2_HUMAN) -  Cannabinoid receptor 2 from Homo sapiens

Seq: 360 a.a.

Struc: 287 a.a.

Protein chain

No UniProt id for this chain

Struc: 230 a.a.

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????