PDBsum entry 8wgc

Membrane protein

PDB id: 8wgc

Contents

Protein chains

762 a.a.

783 a.a.

Ligands

W92

PDB id:

8wgc

Name:

Membrane protein

Title:

Heterodimer of mglu2 and mglu4 bound with mglu2 agonist ly379268

Structure:

Metabotropic glutamate receptor 2. Chain: d. Engineered: yes. Metabotropic glutamate receptor 4. Chain: a. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: grm2. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Gene: grm4. Expression_system_cell_line: hek293

Authors:

Y.Zhang,J.Liu

Key ref:

Y.Zhang and j.liu Structural basis of orientated asymmetry in a mglu heterodimer. To be published, . PubMed id: 39609406

Date:

20-Sep-23 Release date: 27-Nov-24

Protein chain

Q14416  (GRM2_HUMAN) -  Metabotropic glutamate receptor 2 from Homo sapiens

Seq: 872 a.a.

Struc: 762 a.a.

Protein chain

Q14833  (GRM4_HUMAN) -  Metabotropic glutamate receptor 4 from Homo sapiens

Seq: 912 a.a.

Struc: 783 a.a.