PDBsum entry 8wdt

Membrane protein

PDB id: 8wdt

Contents

Protein chains

297 a.a.

213 a.a.

224 a.a.

Ligands

WCH

PDB id:

8wdt

Name:

Membrane protein

Title:

Crystal structure of the human adenosine a2a receptor in complex with photoresponsive ligand photoneca(blue)

Structure:

Adenosine receptor a2a. Chain: a. Engineered: yes. Antibody fab fragment light chain. Chain: b. Antibody fab fragment heavy chain. Chain: c

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: adora2a. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Mus musculus. Organism_taxid: 10090. Organism_taxid: 10090

Resolution:

3.34Å R-factor: 0.219 R-free: 0.266

Authors:

T.Araya,H.Asada,S.Iwata,D.H.Im

Key ref:

T.Araya et al. (2023). Crystal structure reveals the binding mode and select of a photoswitchable ligand for the adenosine a 2a re. Biochem biophys res commun, 695, 49393. PubMed id: 38171234

Date:

16-Sep-23 Release date: 17-Jan-24

Protein chain

P29274  (AA2AR_HUMAN) -  Adenosine receptor A2a from Homo sapiens

Seq: 412 a.a.

Struc: 297 a.a.*

Protein chain

No UniProt id for this chain

Struc: 213 a.a.

Protein chain

No UniProt id for this chain

Struc: 224 a.a.

* PDB and UniProt seqs differ at 5 residue positions (black crosses)