PDBsum entry 8vhf

Membrane protein/signaling protein

PDB id: 8vhf

Contents

Protein chains

339 a.a.

56 a.a.

129 a.a.

237 a.a.

296 a.a.

Ligands

8VP

PDB id:

8vhf

Name:

Membrane protein/signaling protein

Title:

Cryo-em structure of gpr119-gs-nb35 complex with small molecule agonist mbx-2982

Structure:

Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1, hibit. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2. Chain: c. Synonym: g gamma-i.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnb1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Gene: gng2. Lama glama.

Authors:

D.-G.Kim,V.Cherezov

Date:

01-Jan-24 Release date: 30-Oct-24

Protein chain

No UniProt id for this chain

Struc: 339 a.a.

Protein chain

No UniProt id for this chain

Struc: 56 a.a.

Protein chain

No UniProt id for this chain

Struc: 129 a.a.

Protein chain

P97481  (EPAS1_MOUSE) -  Endothelial PAS domain-containing protein 1 from Mus musculus

Seq: 874 a.a.

Struc: 237 a.a.*

Protein chain

No UniProt id for this chain

Struc: 296 a.a.

* PDB and UniProt seqs differ at 187 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????