 |
PDBsum entry 8t1w
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Membrane protein
|
PDB id
|
|
|
|
8t1w
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Membrane protein
|
|
|
Title:
|
|
Crystal structure of orphan g protein-coupled receptor 6 with bound cvn424
|
|
Structure:
|
|
G-protein coupled receptor 6, soluble cytochrome b562 chimera. Chain: a. Synonym: sphingosine 1-phosphate receptor gpr6,cytochrome b-562. Engineered: yes
|
|
Source:
|
|
Homo sapiens, escherichia coli. Human. Organism_taxid: 9606, 562. Gene: gpr6, cybc. Expressed in: homo sapiens. Expression_system_taxid: 9606
|
|
Resolution:
|
|
|
3.49Å
|
R-factor:
|
0.293
|
R-free:
|
0.322
|
|
|
Authors:
|
|
M.Barekatain,L.Johansson,J.H.Lam,A.V.Sadybekov,G.W.Han,P.Popov, J.Russo,J.Bliesath,N.Brice,M.Beresford,L.Carlson,K.S.Saikatendu, H.Sun,S.Murphy,H.Monenschein,H.H.Schiffer,C.Lutomski,C.V.Robinson, Z.Liu,T.Hua,V.Katritch,V.Cherezov
|
|
Key ref:
|
|
M.Barekatain
et al.
Structural insights into the high basal activity and agonism of the orphan receptor gpr6 implicated in parkinson'S disease.
Sci signal,
.
PubMed id:
|
|
|
Date:
|
|
|
04-Jun-23
|
Release date:
|
04-Dec-24
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
Links
