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PDBsum entry 8t1v
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Membrane protein
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PDB id
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8t1v
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PDB id:
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Membrane protein
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Title:
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Crystal structure of orphan g protein-coupled receptor 6 with bound inverse agonist 3h
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Structure:
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G-protein coupled receptor 6, soluble cytochrome b562 chimera. Chain: a. Synonym: sphingosine 1-phosphate receptor gpr6,cytochrome b-562. Engineered: yes
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Source:
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Homo sapiens, escherichia coli. Human. Organism_taxid: 9606, 562. Gene: gpr6, cybc. Expressed in: homo sapiens. Expression_system_taxid: 9606
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Resolution:
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2.60Å
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R-factor:
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0.233
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R-free:
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0.258
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Authors:
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M.Barekatain,L.Johansson,J.H.Lam,A.V.Sadybekov,G.W.Han,P.Popov, J.Russo,J.Bliesath,N.Brice,M.Beresford,L.Carlson,K.S.Saikatendu, H.Sun,S.Murphy,H.Monenschein,H.H.Schiffer,C.Lutomski,C.V.Robinson, Z.Liu,T.Hua,V.Katritch,V.Cherezov
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Key ref:
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M.Barekatain
et al.
Structural insights into the high basal activity and agonism of the orphan receptor gpr6 implicated in parkinson'S disease.
Sci signal,
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PubMed id:
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Date:
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04-Jun-23
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Release date:
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04-Dec-24
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PROCHECK
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Headers
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References
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Links
