PDBsum entry 8k6n

Membrane protein

PDB id: 8k6n

Contents

Protein chains

225 a.a.

340 a.a.

57 a.a.

31 a.a.

301 a.a.

232 a.a.

PDB id:

8k6n

Name:

Membrane protein

Title:

Structural complex of neuropeptide y receptor 2

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-2. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Mutation: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai2, gnai2b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Synthetic: yes.

Authors:

S.Y.Shen,C.Zhao,Z.H.Shao

Key ref:

S.Y.Shen and z.h.shao Structural complex of neuropeptide y receptor 2. To be published, . PubMed id: 38882210

Date:

25-Jul-23 Release date: 31-Jul-24

Protein chain

P04899  (GNAI2_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-2 from Homo sapiens

Seq: 355 a.a.

Struc: 225 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 340 a.a.*

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 57 a.a.

Protein chain

P01303  (NPY_HUMAN) -  Pro-neuropeptide Y from Homo sapiens

Seq: 97 a.a.

Struc: 31 a.a.

Protein chain

P49146  (NPY2R_HUMAN) -  Neuropeptide Y receptor type 2 from Homo sapiens

Seq: 381 a.a.

Struc: 301 a.a.

Protein chain

No UniProt id for this chain

Struc: 232 a.a.

* PDB and UniProt seqs differ at 5 residue positions (black crosses)