PDBsum entry 8k5c

Membrane protein

PDB id: 8k5c

Contents

Protein chain

291 a.a.

Ligands

OJX

PDB id:

8k5c

Name:

Membrane protein

Title:

Cryo-em structure of acipimox bound human hydroxy-carboxylic acid receptor 2 (local refinement)

Structure:

Human hydroxycarboxylic acid receptor 2. Chain: a. Synonym: g-protein coupled receptor 109a,g-protein coupled receptor hm74a,niacin receptor 1,nicotinic acid receptor. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hcar2, hca2. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108

Authors:

J.H.Park,N.Ishimoto,S.Y.Park

Key ref:

J.H.Park et al. (2023). Structural basis for ligand recognition and signaling hydroxy-Carboxylic acid receptor 2. Nat commun, 14, 7150. PubMed id: 37932263

Date:

21-Jul-23 Release date: 22-Nov-23

Protein chain

Q8TDS4  (HCAR2_HUMAN) -  Hydroxycarboxylic acid receptor 2 from Homo sapiens

Seq: 363 a.a.

Struc: 291 a.a.