PDBsum entry 8jxt

Membrane protein

PDB id: 8jxt

Contents

Protein chains

218 a.a.

337 a.a.

52 a.a.

230 a.a.

270 a.a.

Ligands

HSM

PO4

PDB id:

8jxt

Name:

Membrane protein

Title:

Histamine-bound h4r/gi complex

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: b. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Mutation: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: c. Synonym: transducin beta chain 1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Gene: hrh4, gpcr105.

Authors:

Y.He,R.Xia

Key ref:

Y.He and r.xia Histamine-Bound h4r/gi complex. To be published, . PubMed id: 38509098

Date:

01-Jul-23 Release date: 20-Mar-24

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 218 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 337 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 52 a.a.

Protein chain

No UniProt id for this chain

Struc: 230 a.a.

Protein chain

Q9H3N8  (HRH4_HUMAN) -  Histamine H4 receptor from Homo sapiens

Seq: 390 a.a.

Struc: 270 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain B: E.C.3.6.5.- - ?????