PDBsum entry 8jxr

Membrane protein

PDB id: 8jxr

Contents

Protein chains

270 a.a.

124 a.a.

341 a.a.

202 a.a.

171 a.a.

Ligands

GLC-GLC

7LD

PDB id:

8jxr

Name:

Membrane protein

Title:

Structure of nanobody-bound drd1_lsd complex

Structure:

D(1a) dopamine receptor. Chain: a. Synonym: dopamine d1 receptor, drd1. Engineered: yes. Mutation: yes. Nba3. Chain: b. Engineered: yes. Maltose/maltodextrin-binding periplasmic protein,

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: drd1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Escherichia coli o157:h7, staphylococcus aureus, staphylococcus aureus subsp. Aureus mu50, streptococcus sp. 'Group g'.

Authors:

Y.Zhuang,Y.Xu,L.Fan,S.Wang,H.E.Xu

Key ref:

L.Fan et al. Structural basis of psychedelic lsd recognition at do d 1 receptor.. Neuron, . PubMed id: 39094559

Date:

01-Jul-23 Release date: 04-Sep-24

Protein chain

P21728  (DRD1_HUMAN) -  D(1A) dopamine receptor from Homo sapiens

Seq: 446 a.a.

Struc: 270 a.a.*

Protein chain

No UniProt id for this chain

Struc: 124 a.a.

Protein chain

P06654  (SPG1_STRSG) -  Immunoglobulin G-binding protein G from Streptococcus sp. group G

Seq: 448 a.a.

Struc: 341 a.a.*

Protein chain

P0A015  (SPA_STAAM) -  Immunoglobulin G-binding protein A from Staphylococcus aureus (strain Mu50 / ATCC 700699)

Seq: 450 a.a.

Struc: 341 a.a.*

Protein chain

P0AEX9  (MALE_ECOLI) -  Maltose/maltodextrin-binding periplasmic protein from Escherichia coli (strain K12)

Seq: 396 a.a.

Struc: 341 a.a.*

Protein chain

No UniProt id for this chain

Struc: 202 a.a.

Protein chain

No UniProt id for this chain

Struc: 171 a.a.

* PDB and UniProt seqs differ at 523 residue positions (black crosses)