PDBsum entry 8jpp

Membrane protein

PDB id: 8jpp

Contents

Protein chains

237 a.a.

331 a.a.

49 a.a.

305 a.a.

Ligands

SIN

PDB id:

8jpp

Name:

Membrane protein

Title:

Cryo-em structure of succinate receptor bound to succinate acid coupling minigsq

Structure:

Guanine nucleotide-binding protein g(s) subunit alpha isoforms short. Chain: a. Synonym: adenylate cyclase-stimulating g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnas, gnas1, gsp. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gnb1. Gene: gng2. Expression_system_taxid: 7108.

Authors:

T.X.Wang,W.Q.Tang,F.H.Li,J.Y.Wang

Key ref:

T.Wang et al. Molecular activation and g protein coupling selectivi human succinate receptor sucr1.. Cell res, . PubMed id: 38744983

Date:

12-Jun-23 Release date: 22-May-24

Protein chain

P63092  (GNAS2_HUMAN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Homo sapiens

Seq: 394 a.a.

Struc: 237 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 331 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 49 a.a.

Protein chain

P0ABE7  (C562_ECOLX) -  Soluble cytochrome b562 from Escherichia coli

Seq: 128 a.a.

Struc: 305 a.a.*

Protein chain

Q9BXA5  (SUCR1_HUMAN) -  Succinate receptor 1 from Homo sapiens

Seq: 334 a.a.

Struc: 305 a.a.

* PDB and UniProt seqs differ at 91 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????