PDBsum entry 8jhc

Membrane protein

PDB id: 8jhc

Contents

Protein chains

429 a.a.

225 a.a.

120 a.a.

212 a.a.

PDB id:

8jhc

Name:

Membrane protein

Title:

Fzd3 in inactive state

Structure:

Frizzled-3,soluble cytochrome b562. Chain: r. Synonym: fz-3,hfz3. Engineered: yes. Other_details: inactive fzd3. Anti-bril fab heavy chain. Chain: h. Engineered: yes. Anti-fab nanobody.

Source:

Homo sapiens, escherichia coli. Organism_taxid: 9606, 562. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Homo sapiens. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.

Authors:

F.Xu,Z.Zhang

Key ref:

Z.Zhang et al. (2024). A framework for frizzled-G protein coupling and impli to the pcp signaling pathways.. Cell discov, 10, 3. PubMed id: 38182578

Date:

23-May-23 Release date: 17-Jan-24

Protein chain

P0ABE7  (C562_ECOLX) -  Soluble cytochrome b562 from Escherichia coli

Seq: 128 a.a.

Struc: 429 a.a.*

Protein chain

Q9NPG1  (FZD3_HUMAN) -  Frizzled-3 from Homo sapiens

Seq: 666 a.a.

Struc: 429 a.a.*

Protein chain

No UniProt id for this chain

Struc: 225 a.a.

Protein chain

No UniProt id for this chain

Struc: 120 a.a.

Protein chain

No UniProt id for this chain

Struc: 212 a.a.

* PDB and UniProt seqs differ at 122 residue positions (black crosses)