PDBsum entry 8jh7

Membrane protein

PDB id: 8jh7

Contents

Protein chains

225 a.a.

120 a.a.

212 a.a.

431 a.a.

PDB id:

8jh7

Name:

Membrane protein

Title:

Fzd6 in inactive state

Structure:

Anti-bril fab heavy chain. Chain: h. Engineered: yes. Anti-fab nanobody. Chain: k. Engineered: yes. Anti-bril fab light chain. Chain: l. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: hi5. Synthetic construct. Organism_taxid: 32630. Expressed in: escherichia coli.

Authors:

F.Xu,Z.Zhang

Key ref:

Z.Zhang et al. (2024). A framework for frizzled-G protein coupling and impli to the pcp signaling pathways.. Cell discov, 10, 3. PubMed id: 38182578

Date:

22-May-23 Release date: 17-Jan-24

Protein chain

No UniProt id for this chain

Struc: 225 a.a.

Protein chain

No UniProt id for this chain

Struc: 120 a.a.

Protein chain

No UniProt id for this chain

Struc: 212 a.a.

Protein chain

O60353  (FZD6_HUMAN) -  Frizzled-6 from Homo sapiens

Seq: 706 a.a.

Struc: 431 a.a.*

Protein chain

P0ABE7  (C562_ECOLX) -  Soluble cytochrome b562 from Escherichia coli

Seq: 128 a.a.

Struc: 431 a.a.*

* PDB and UniProt seqs differ at 121 residue positions (black crosses)