PDBsum entry 8iw4

Membrane protein

PDB id: 8iw4

Contents

Protein chains

179 a.a.

302 a.a.

35 a.a.

296 a.a.

233 a.a.

Ligands

SPD

PDB id:

8iw4

Name:

Membrane protein

Title:

Cryo-em structure of the spe-bound mtaar9-gs complex

Structure:

Guanine nucleotide-binding protein g(s) subunit alpha isoforms short. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Engineered: yes. Other_details: author stated: residues (-9) - (-4) is his tag,

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Mus musculus. House mouse.

Authors:

J.P.Sun,Q.Li,F.Yang,Y.F.Xu,L.L.Guo,S.Lian,M.H.Zhang,N.K.Rong

Key ref:

L.Guo et al. Structural basis of amine odorant perception by a mam olfactory receptor.. Nature, . PubMed id: 37225986

Date:

29-Mar-23 Release date: 31-May-23

Protein chain

P63092  (GNAS2_HUMAN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Homo sapiens

Seq: 394 a.a.

Struc: 179 a.a.*

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 179 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 302 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 35 a.a.

Protein chain

Q5QD04  (TAAR9_MOUSE) -  Trace amine-associated receptor 9 from Mus musculus

Seq: 348 a.a.

Struc: 296 a.a.

Protein chain

No UniProt id for this chain

Struc: 233 a.a.

* PDB and UniProt seqs differ at 171 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????