PDBsum entry 8ikh

Membrane protein

PDB id: 8ikh

Contents

Protein chains

217 a.a.

333 a.a.

53 a.a.

265 a.a.

223 a.a.

Ligands

Q2L

PDB id:

8ikh

Name:

Membrane protein

Title:

Cryo-em structure of human receptor with g proteins

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Expressed in: insect cell expression vector ptie1.

Authors:

S.Y.Shen,Z.H.Shao

Key ref:

S.Y.Shen and z.h.shao Cryo-Em structure of human receptor with g proteins. To be published, . PubMed id: 38830102

Date:

28-Feb-23 Release date: 05-Jun-24

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 217 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 333 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 53 a.a.

Protein chain

P21554  (CNR1_HUMAN) -  Cannabinoid receptor 1 from Homo sapiens

Seq: 472 a.a.

Struc: 265 a.a.

Protein chain

No UniProt id for this chain

Struc: 223 a.a.

Enzyme reactions

• Enzyme class: Chains A, B, C, R: E.C.?