PDBsum entry 8ha0

Lipid binding protein/hormone/immune sys

PDB id: 8ha0

Contents

Protein chains

235 a.a.

341 a.a.

57 a.a.

129 a.a.

34 a.a.

359 a.a.

Ligands

CLR ×4

PLM ×3

PDB id:

8ha0

Name:

Lipid binding protein/hormone/immune sys

Title:

Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1

Structure:

Guanine nucleotide-binding protein g(s) subunit alpha. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit

Source:

Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: gnb1.

Authors:

L.Zhao,H.E.Xu,Q.Yuan

Key ref:

L.H.Zhao et al. (2023). Molecular recognition of two endogenous hormones by t human parathyroid hormone receptor-1.. Acta pharmacol sin, 44, 1227. PubMed id: 36482086

Date:

26-Oct-22 Release date: 21-Dec-22

Protein chain

No UniProt id for this chain

Struc: 235 a.a.

Protein chain

P54311  (GBB1_RAT) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Rattus norvegicus

Seq: 340 a.a.

Struc: 341 a.a.

Protein chain

P63212  (GBG2_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Bos taurus

Seq: 71 a.a.

Struc: 57 a.a.

Protein chain

No UniProt id for this chain

Struc: 129 a.a.

Protein chain

P01270  (PTHY_HUMAN) -  Parathyroid hormone from Homo sapiens

Seq: 115 a.a.

Struc: 34 a.a.

Protein chain

Q03431  (PTH1R_HUMAN) -  Parathyroid hormone/parathyroid hormone-related peptide receptor from Homo sapiens

Seq: 593 a.a.

Struc: 359 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)