PDBsum entry 7xw3

Gene regulation

PDB id: 7xw3

Contents

Protein chain

1502 a.a.

PDB id:

7xw3

Name:

Gene regulation

Title:

Cryo-em structure of an apo-form of human dicer

Structure:

Endoribonuclease dicer. Chain: a. Synonym: helicase with rnase motif,helicase moi. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: dicer1, dicer, herna, kiaa0928. Expressed in: homo sapiens. Expression_system_taxid: 9606

Authors:

H.Lee,S.-H.Roh

Key ref:

Y.Y.Lee et al. Structure of the human dicer-Pre-Mirna complex in a d state.. Nature, . PubMed id: 36813958

Date:

26-May-22 Release date: 08-Mar-23

Protein chain

Q9UPY3  (DICER_HUMAN) -  Endoribonuclease Dicer from Homo sapiens

Seq: 1922 a.a.

Struc: 1502 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.26.3 - ribonuclease Iii.
• Reaction: Endonucleolytic cleavage to 5'-phosphomonoester.