PDBsum entry 7x5e

Transcription/DNA

PDB id: 7x5e

Contents

Protein chains

99 a.a.

106 a.a.

DNA/RNA

Ligands

P6G

Waters ×168

PDB id:

7x5e

Name:

Transcription/DNA

Title:

Nrf2-mafg heterodimer bound with csmbe1

Structure:

Transcription factor mafg. Chain: a, e. Synonym: v-maf musculoaponeurotic fibrosarcoma oncogene homolog g, hmaf. Engineered: yes. Nuclear factor erythroid 2-related factor 2. Chain: b, f. Synonym: nf-e2-related factor 2,nfe2-related factor 2,nrf-2,hebp1, nuclear factor,erythroid derived 2,like 2.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: mafg. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: nrf2. Synthetic: yes. Synthetic construct.

Resolution:

2.30Å R-factor: 0.215 R-free: 0.242

Authors:

T.Sengoku,M.Shiina,K.Suzuki,K.Hamada,K.Sato,A.Uchiyama,C.Okada, S.Baba,T.Ohta,H.Motohashi,M.Yamamoto,K.Ogata

Key ref:

T.Sengoku et al. Structural basis of transcription regulation by cnc f transcription factor, Nrf2. Nucleic acids res, . PubMed id: 36454022

Date:

04-Mar-22 Release date: 09-Nov-22

Protein chains

O15525  (MAFG_HUMAN) -  Transcription factor MafG from Homo sapiens

Seq: 162 a.a.

Struc: 99 a.a.

Protein chains

Q16236  (NF2L2_HUMAN) -  Nuclear factor erythroid 2-related factor 2 from Homo sapiens

Seq: 605 a.a.

Struc: 106 a.a.

DNA/RNA chains

G-T-T-G-C-T-G-A-C-T-C-A-T-C-A-T 16 bases

C-A-T-G-A-T-G-A-G-T-C-A-G-C-A-A 16 bases

G-T-T-G-C-T-G-A-C-T-C-A-T-C-A-T 16 bases

C-A-T-G-A-T-G-A-G-T-C-A-G-C-A-A 16 bases